Project participants

Jean-Philippe Lambert^1*, Gordana Ivosev^2*, Amber L. Couzens¹, Brett Larsen1, Mikko Taipale³, Zhen-Yuan Lin¹, Quan Zhong⁴, Susan Lindquist^3,5, Marc Vidal⁴, Ruedi Aebersold⁶, Tony Pawson^1,7, Ron Bonner², Stephen Tate^2** and Anne-Claude Gingras^1,7**

1. Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto M5G 1X5, Canada.
2. AB Sciex, 71 Four Valley Drive, Concord, Ontario, L4K 4V8, Canada
3. Whitehead Institute for Biomedical Research, Cambridge, MA 02142
4. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
5. Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 and Howard Hughes Medical Institute, Cambridge, MA 02139
6. Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland; Competence Center for Systems Physiology and Metabolic Diseases, 8093 Zurich, Switzerland; Faculty of Science, University of Zurich, 8057 Zurich, Switzerland
7. Department of Molecular Genetics, University of Toronto, Toronto M5S 1A8, Canada.

Please send correspondence to:
Stephen Tate, Stephen.Tate@absciex.com
or
Anne-Claude Gingras, gingras@lunenfeld.ca

AUTHOR CONTRIBUTIONS
J.-P.L. generated all CDK4 samples and performed validation experiments; A.L.C. generated all GRK6 samples and performed validation experiments; M.T. performed LUMIER analysis and provided constructs; Z.-Y.L. prepared samples for mass spectrometry; B.L. performed mass spectrometric measurements; G.I. developed and performed statistical analysis; Q.Z. and M.V. provided initial constructs and input on the project; S.L. supervised M.T. and T.P. cosupervised J.-P.L; R.A., R.B. and S.T. developed the SWATH approach; J.-P.L., A.L.C., B.L., A.-C.G., G.I. and S.T. analyzed the SWATH data; .A-C.G. wrote the manuscript with input from all authors; A.-C.G. conceived the study and directed the project.