Welcome to the ProHits-web interaction proteomics repository, initiated by the Gingras lab. We created this repository to store and disseminate AP-MS data generated by us and our collaborators. We record quantitative information and SAINT scoring results, alongside experimental description, and provide supplementary data for each of the studies linked through the repository. The database is searchable, enabling look up proteins of interest across available datasets.While interaction results are listed in a tabular format, multiple baits can be selected for analysis using the visualization tools at ProHits-viz [ProHits-viz]

The database is meant to act as a complement to excellent resources for raw mass spectrometry data [MassIVE] and general protein interaction repositories [BioGRID, IntAct] in which we are also submitting high-confidence interaction lists. Please note that our negative control runs are also contributed to the Contaminant Repository for Affinity Purification [CRAPome].

We are opening for public use all published datasets; unpublished data are password-protected. A quick guide for using the resource can be found [here]. Please contact us if you need any additional information or if there are any issues with the website.